Welcome to the Summer 2011 IMMH Newsletter!


IMMH is about giving people treatment options. Currently, treatment for mental health issues revolves around drug therapy. Not everyone responds well to drug treatments and many prefer not to go this route.

IMMH is about sharing information with people suffering from these disorders and the physicians who treat them. We want to educate practitioners so they are able to provide more options for their patients. And most importantly, IMMH helps patients find doctors through the Clinician Registry so they have more options for treatment.


Clinician Registry eligibility is exclusive to practitioners who have attended an IMMH Conference. In some cases, entry is granted after viewing an IMMH Conference DVD and submitting the corresponding waiver.


Please feel free to share this information with anyone who might find it useful.


"The Breakthrough Depression Solution

A Personalized 9-Step Method for Beating the Physical Causes of Your Depression"

James Greenblatt, MD

Excerpt from page 18


Food Allergies and Depression


People who struggle with food allergies or food intolerances tend to suffer from more depression than their healthy peers. It is unclear which psychological changes are secondary to nutritional deficiencies and/or inflammation. In many cases, the depression improves when the food allergies are treated.


Although there is insufficient research, years of clinical experience have convinced me that food allergies are contributing factors to many psychiatric illnesses, including ADHD, anxiety, and particularly depression. The medical profession has minimized and dismissed this association for many years. A simple blood test can help determine food sensitivities. Although testing is not always 100 percent reliable, it does serve as a guide. Elimination diets, in which limited diets are used to determine sensitivity to offending foods as new foods are introduced one at a time, are another way of determining if you are sensitive to particular foods.


Order your copy of Dr. Greenblatt's book



Increased Protein Digestion Reduces Food Allergenicity

Devin Houston, PhD


Food intake, considered a pleasure by most, also represents a health hazard in situations where metabolism is altered or if food proteins are recognized as harmful by the immune system. In the latter case, IgG, IgE and IgA antibodies are produced by the immune system in response to the food “attack”. The number of food-allergic patients is increasing, as is the severity of the reactions. The effects range from mild rashes, diarrhea, and/or migraine headaches to all-out systemic dysfunction. 


One of the functions of the digestive tract is to change food into a substance that won’t trigger the immune system to launch an attack. Several methods are used in the body to accomplish this task. Stomach acid denatures food proteins. Denaturation removes the “glue” holding the structure of the food protein together and often results in loss of any function associated with the protein. However, even denatured proteins can be allergenic. The next and most definitive step for rendering food proteins harmless is enzymatic degradation which begins in the stomach but predominates in the small intestine. Denaturation actually sets up the protein for optimal break down by protease enzymes. 


The immune system in the gut is triggered by a number of factors but size of the offending protein is the most predominant. The larger the protein, the more likely it is to set off the alarm for IgG antibody production. Conversely, smaller proteins or fragment are able to slip under the radar for immunity activation. Research from several labs demonstrate that when protein digestion is compromised antibody production to that food protein increases.1-3


A compromised digestive system can occur easier than one may think. The simple act of taking an antacid reduces the activity of pepsin, the major protease enzyme in the stomach, by raising the pH of the stomach over 5.0. Many on H2 blockers have increased food allergy symptoms because the resulting low stomach acid fails to activate the pepsin enzyme system. Larger food protein fragments are then passed on to the intestinal tract and have the potential to become allergens.2-4 Conversely, research indicates that pre-treatment of food proteins with protease enzymes results in a less allergenic potential.5, 6 Heating of a protein alone will not break down a food protein sufficiently, so cooking is no guarantee of allergy prevention. 


The World Health Organization proposed in 2001 that food proteins be tested for the allergenic potential. One of the parameters for consideration is the resistance to enzymatic digestion by some food proteins.7 A positive association was found between resistance to digestion and development of food allergy. Food proteins with a high content of proline amino acids, like gluten, are very difficult to digest by human digestive enzymes.


What does this mean for the consumer? Obviously, increasing the digestion of food proteins decreases the chances of potential allergy development. Unfortunately, our own digestive enzymes are not always sufficient. By supplementing with additional acid-stable enzymes from plant sources we can increase the chance of food proteins being sufficiently degraded. These “outside” sourced enzymes are compatible with our digestive systems but have additional properties that provide us with more thorough digestion. The use of supplemental enzymes increases the bioavailability of food nutrients to our system, provides a healthier environment for the probiotic bacteria in our gut, and eliminates the unwelcome side effects of unhealthy digestion, such as fermentation, gas, and bloating.



Oral tolerance of food proteins is an important aspect of our digestive and immune system. The use of over-the-counter enzyme supplements specifically formulated for protein digestion (such as AFP Peptizyde from Houston Enzymes) may further increase digestion of food proteins. Broader spectrum enzyme products, such as TriEnza from Houston Enzymes, benefit not only protein digestion, but also breakdown carbohydrates, starches, and fats which can provide substantial relief from digestive issues such as bloating, gas, cramping, constipation/ diarrhea and lethargy.


Order your copy of the

Integrative Medicine for Mental Health

DVD-ROM today!

This 12-hour training for physicians and mental health practitioners provides practical solutions for treating depression, bipolar disorder, anxiety, OCD, and eating disorders. Order now!


Don't Miss the 2nd Annual

IMMH Conference

For Physicians And

Mental Health Practitioners

September 17-18, 2011

Receive a conference brochure by mail



IMMH, Mental Health Conference, Sedona, Arizona September 17-18, 2011


About the Conference

This conference will explore integrative treatments for mental illness and related disorders. This whole body approach works with multiple fields of medicine, nutritional sciences, and community-based resources. Continuing Education and Continuing Medical Education credits are pending.



James Greenblatt, M.D.

William Shaw, Ph.D.

Kurt Woeller, D.O.

Nutritional Factors in Suicide Prevention - FREE Webinar

Thursday, June 9, 2011


Understanding the consequences of deficiencies in essential fats and cholesterol is important for the effective treatment and prevention of depression and suicide. Dr. Greenblatt will also discuss other effective nutritional approaches such as lithium supplementation in the treatment of depression and suicide risk.

Please Note: This webinar is a one-time, live event but will be recorded and available on our website.

The webinar begins promptly at 5pm PST, 7pm CST,  8pm EST.


Register for this Free Webinar

IgG vs IgE

IgE food allergies are an immediate reaction involving the antibody immunoglobulin E (IgE). Traditional symptoms include hives, congestion, and swelling. Some IgE food allergies can be lethal.


IgG food intolerances or sensitivities are delayed reactions, typically two-hours or more after ingestion, involving the antibody immunoglobulin G (IgG). Symptoms can manifest as behavioral problems, hyperactivity, and gastrointestinal discomfort.


The IgG Food Allergy Test is useful for determining offending foods. Elimination of IgG positive foods can improve symptoms of depression, psychosis, violent and aggressive behavior, and AD(H)D.


Please note that these tests require a physician signature to order. If you are a patient and would like to find a physician in your area please visit www.immh.org or call The Great Plains Laboratory, Inc. at 913-341-8949.

What are zeebra formulations all about?
Zeebra formulations is a new product line being distributed exclusively by New Beginnings Nutritionals. This product line is designed to meet the unique needs of individuals who suffer from a variety of mental health related disorders including depression, anxiety, bi-polar, OCD, eating disorders, and others. 


These new products and formulations are made available under the careful direction of Dr. James Greenblatt, a child and adult psychiatrist who has been successfully treating patients with mental health disorders - for over 20 years - using an integrative medical approach.


Visit the Mental Health Support product category from New Beginnings Nutritionals for a comprehensive list of supporting products.

Want to link to IMMH.org?

Help us spread the word! Simply copy the image below and embed the following link www.immh.org



1.     Anthoni S, Savilahti E, et al.  Milk protein IgG and IgA: The association with milk-induced gastrointestinal symptoms in adultsWorld J Gastroenterol 2009; 15:4915-4918.

2.     Schmidt DG, Meijer RJ, et al. Raising the pH of the pepsin-catalyzed hydrolysis of bovine whey proteins increases the antigenicity of the hydrolysatesClin Exp Allergy 1995; 25(10):1007-17.

3.     Untersmayr E, Scholl I, et al.  Antacid medication inhibits digestion of dietary proteins and causes food allergy: a fish allergy model in BALB/c miceJ Allergy Clin Immunol 2003; 112(3):616-23.

4.     Untersmayr E and Jensen-Jarolim, E.  The role of protein digestibility and antacids on food allergy outcomes.  J Allergy Clin Immunol 2008; 121(6):1301-10.

5.     Kim SB, Ki KS, et al.  Peptic and tryptic hydrolysis of native and heated whey protein to reduce its antigenicityJ Dairy Sci 2007; 90(9):4043-50.

6.     Burks AW, Williams LW, et al.  Allergenicity of peanut and soybean extracts altered by chemical or thermal denaturation in patients with atopic dermatitis and positive food challengesJ. Allergy Clin Immunol 1992; 90(6 Pt 1):889-97.

7.     Bannon G, Fu T-J, et al.  Protein digestibility and relevance to allergenicity.  Environ Health Perspect 2003; 111:1122-24.